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igf binding protein 5  (R&D Systems)


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    Structured Review

    R&D Systems igf binding protein 5
    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding <t>protein</t> <t>5</t> (IGFBP-5) (ng/mL).
    Igf Binding Protein 5, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/igf binding protein 5/product/R&D Systems
    Average 94 stars, based on 8 article reviews
    igf binding protein 5 - by Bioz Stars, 2026-05
    94/100 stars

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    1) Product Images from "Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass"

    Article Title: Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass

    Journal: Journal of the Endocrine Society

    doi: 10.1210/jendso/bvag003

    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding protein 5 (IGFBP-5) (ng/mL).
    Figure Legend Snippet: Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding protein 5 (IGFBP-5) (ng/mL).

    Techniques Used: Biomarker Discovery, Control, Binding Assay



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    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding <t>protein</t> <t>5</t> (IGFBP-5) (ng/mL).
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    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding <t>protein</t> <t>5</t> (IGFBP-5) (ng/mL).
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    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding <t>protein</t> <t>5</t> (IGFBP-5) (ng/mL).
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    Fig. 1. Representative examples of in situ hybridization for IGF-I, <t>IGFBP5</t> and IGF-IR mRNAs for the three studied groups: control animals (C group), animals submitted to the nox- ious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5; IGF-IR: Insulin-like Growth Factor-I Receptor.
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    Fig. 1. Representative examples of in situ hybridization for IGF-I, <t>IGFBP5</t> and IGF-IR mRNAs for the three studied groups: control animals (C group), animals submitted to the nox- ious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5; IGF-IR: Insulin-like Growth Factor-I Receptor.
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    Image Search Results


    Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding protein 5 (IGFBP-5) (ng/mL).

    Journal: Journal of the Endocrine Society

    Article Title: Subclinically low BMD in young men is associated with compromised bone microarchitecture and lower lean mass

    doi: 10.1210/jendso/bvag003

    Figure Lengend Snippet: Biomarkers. Fig. 1 depicts all assessed biomarker concentrations. The total hip, femoral neck, or lumbar spine (Lower) group is depicted in black filled circles, while the control (Con) group is in clear squares. A, P1NP (pg/mL); B, alkaline phosphatase (ALP) (pg/mL); C, tartrate-resistant acid phosphatase 5b (TRAP5b) (U/L); D, sclerostin (pmol/L); E, β C-terminal cross-linked telopeptide of type I collagen (βCTX) (pmol/L); F, testosterone (ng/mL); G, estradiol (pg/mL); H, parathyroid hormone (PTH) (pg/mL); I, insulin-like growth factor-1 (IGF-1) (ng/mL); J, insulin-like growth factor-1 binding protein 5 (IGFBP-5) (ng/mL).

    Article Snippet: Commercially available enzyme-linked immunosorbent assays were used to determine circulating concentrations of serum procollagen type I N-terminal propeptide (PINP; Novus catalog No. NBP2-76465, RRID:AB_3720306, 1:200 dilution, CV 5.3%, sensitivity 9.4 pg/mL), alkaline phosphatase (ALP; Novus catalog No. NBP2-68197, RRID:AB_3720307, CV 6.0%, sensitivity 46.9 pg/mL), tartrate-resistant acid phosphatase 5b (TRAP5b; Immunodiagnostic Systems catalog No. SB-TR201A, RRID:AB_3095995, CV 4.7%, sensitivity 0.4 U/L), sclerostin (Biomedica catalog No. BI-20492, RRID:AB_2894889, CV 6.4%, sensitivity 3.2 pmol/L), testosterone (Alpco Diagnostics catalog No. 11-TESHU-E01, RRID:AB_3720308, CV 4.2%, sensitivity 0.02 ng/mL), estradiol (Alpco Diagnostics catalog No. 11-ESTHU-E01, RRID:AB_2756385, CV 7.6%, sensitivity 10 pg/mL), insulin like growth factor-1 (IGF-1; Alpco Diagnostics catalog No. 22-IGFHU-E01, RRID:AB_2923276, 1:20 dilution, average CV 3.3%, assay sensitivity 9.4 pg/mL), IGF binding protein-5 (IGFBP-5; R and D Systems catalog No. DY875, RRID:AB_3720311, 3× dilution, CV 2.7%), parathyroid hormone (PTH; (Alpco Diagnostics catalog No. 21-IPTHU-E01, RRID:AB_2943035), CV 7.3%, sensitivity 1.6 pg/mL), and plasma β C-terminal cross-linked telopeptide of type I collagen (βCTX; Immunodiagnostic Systems catalog No. IS-3000N, RRID:AB_3720313, CV 6.2%, sensitivity 3.2 pmol/L).

    Techniques: Biomarker Discovery, Control, Binding Assay

    Fig. 1. Representative examples of in situ hybridization for IGF-I, IGFBP5 and IGF-IR mRNAs for the three studied groups: control animals (C group), animals submitted to the nox- ious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5; IGF-IR: Insulin-like Growth Factor-I Receptor.

    Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

    Article Title: Growth cartilage expression of growth hormone/insulin-like growth factor I axis in spontaneous and growth hormone induced catch-up growth.

    doi: 10.1016/j.ghir.2012.04.004

    Figure Lengend Snippet: Fig. 1. Representative examples of in situ hybridization for IGF-I, IGFBP5 and IGF-IR mRNAs for the three studied groups: control animals (C group), animals submitted to the nox- ious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5; IGF-IR: Insulin-like Growth Factor-I Receptor.

    Article Snippet: Immunohistochemical staining was performed in PFA-fixed frontal sections (5 μm thick) of proximal tibiae, using IGF-I and IGF binding protein 5 (IGFBP5) polyclonal antibodies (Santa Cruz Biotechnology Inc, CA, USA) as described elsewhere [27].

    Techniques: In Situ Hybridization, Control, Binding Assay

    Fig. 2. Representative examples of immunohistochemistry for IGF-I and IGFBP5 for the three studied groups: control animals (C group), animals submitted to the noxious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). A negative control is also presented. IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5.

    Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

    Article Title: Growth cartilage expression of growth hormone/insulin-like growth factor I axis in spontaneous and growth hormone induced catch-up growth.

    doi: 10.1016/j.ghir.2012.04.004

    Figure Lengend Snippet: Fig. 2. Representative examples of immunohistochemistry for IGF-I and IGFBP5 for the three studied groups: control animals (C group), animals submitted to the noxious stimulus (CR group), and animals submitted to the noxious stimulus treated with growth hormone (CRGH group). A negative control is also presented. IGF-I: Insulin-like Growth Factor-I; IGFBP5: Insulin-like Growth Factor Binding Protein 5.

    Article Snippet: Immunohistochemical staining was performed in PFA-fixed frontal sections (5 μm thick) of proximal tibiae, using IGF-I and IGF binding protein 5 (IGFBP5) polyclonal antibodies (Santa Cruz Biotechnology Inc, CA, USA) as described elsewhere [27].

    Techniques: Immunohistochemistry, Control, Negative Control, Binding Assay